4212B Engineering Building III
NC State University
B.M.E. in Mechanical Engineering, Auburn University
M.S. in Mechanical Engineering, Cornell University
Ph.D. in Mechanical Engineering, Cornell University
Post-doctoral Fellowship, Chemistry, University of Michigan
Post-doctoral Fellowship, Orthopaedic Surgery, University of Michigan
The overall goal of Dr. Cole's Orthopaedic Mechanobiology Lab is to determine mechanisms underlying the prevalent bone deficits in various clinical conditions (e.g., stroke, obesity, aging, and nerve injury), with the long-term goal of developing novel therapies to treat or even prevent bone loss in these scenarios. Her lab characterizes changes in the structure and function of bone, muscle, and vascular tissues and cells using high resolution computed tomography, materials characterization techniques (e.g., Raman spectroscopy, mechanical testing), and microscopy. Their work lies at the nexus of regenerative medicine and rehabilitation engineering, determining the factors that lead to degenerated bone tissue and then developing new strategies to restore not only tissue properties but also overall musculoskeletal function.