| Projects |
| (Sort by Personnel) |
| Project Areas:
Tensile Strain Bioreactor Primary Cilia Chondrogenesis Fluid Shear Meniscal Allografts Finite Element Modeling Scaffold Development |
Controlled Release Scaffolds Projects |
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| Overall Project Goal |
The overall goal of the Controlled Release Scaffolds Projects are to create scaffolds with seeded hASC and controlled release drugs for wound healing and tissue engineering applications. | ||
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Researchers & Specific Projects |
Mahsa Mohiti
Mahsa's specific project focuses on developing functional scaffolds from biocompatible polymers using an electrospinning system. The scaffolds are composed of different fiber morphologies such as single component fibers, core-sheath bicomponent fibers and porous fibers. Various drugs such as tricalcium phosphate, for bone tissue engineering, and silver nanoparticles, for wound healing applications, can be loaded within these scaffolds. The release rates of drugs can be controlled distinctively over the therapeutic period. An additional aspect of her research is studying the interaction of variety of cell types with the developed scaffolds in in-vitro andin-vivo situations. Stephen Tuin Stephen's specific project focuses on scale up of hollow nonwoven fibers with interconnected micropores using spun bond technology. Spun bond fibers allow higher throughput, increased mechanical properties, and lower production costs than electrospun fibers. Potential applications include desalinization, gas separation, microfiltration, and tissue engineering scaffolds. Brendan Mckelvy Brendan's specific project focuses on assisting Mahsa in her project by examining the antimicrobial properties of electrospun scaffolds. Shrea Saha Shrea's specific project focuses on methods of delivering Ibuprofen via poly-lactic acid for wound healing applications. Chronic inflammation impedes wound healing; therefore, the incorporation of Ibuprofen into scaffolds could potentially decrease the inflammation and expedite the wound healing process. |
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