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John Cavanagh
John Cavanagh
Adjunct Professor of Biomedical Engineering
William Neal Reynolds Distinguished Professor of Biochemistry
B.Sc., 1985, University of Surrey, UK
Ph.D., 1988, University of Cambridge UK (with James Keeler )
Postdoctoral Fellow, 1988-90, Scripps Research Institute (with Mark Rance )
Royal Society Research Fellow, 1990-91, University of Cambridge, UK
Senior Research Associate, 1991-1994, Scripps Research Institute ( Peter Wright's lab)
Director, 1994-1999, NMR Structural Biology Facility, Wadsworth Center, NYSDO
Professor, 1999-2000, Department of Chemistry, Purdue University
Professor, 2000-present, Department of Molecular and Structural Biochemistry, NCSU
cavanagh-lab.bch.ncsu.edu/
128 Polk Hall
NC State University
(919) 513-4349

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Microsystems Engineering
Bacterial competence, bacterial response and protection, calbindin-D28K.
1. Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing. Ulrich DL, Kojetin D, Bassler BL, Cavanagh J, & Loria JP. J Mol Biol (2005). In press.

2. 1H, 15N, and 13C chemical shift assignments of the Vibrio harveyi histidine phosphotransferase protein LuxU. Ulrich DL, Thompson R, Bassler B, Cavanagh J, & Loria JP. J Biomol NMR (2004) 29, 4: 551-552 [pubmed] [pdf]

3. Evaluation of the DNA binding tendencies of the transition state regulator AbrB. Bobay BG, Benson L, Naylor S, Feeney B, Clark AC, Goshe MB, Strauch MA, Thompson R, & Cavanagh J. Biochemistry (2004) 43, 51: 16106-16118 [pubmed] [pdf]

4. Sub-classification of response regulators using the surface characteristics of their receiver domains. Kojetin DJ, Thompson RJ, & Cavanagh J. FEBS Lett (2003) 554, 3: 231-236 [pubmed] [pdf] [corrigendum] [supplemental data]

5. Macromolecular assembly of the transition state regulator AbrB in its unbound and complexed states probed by microelectrospray ionization mass spectrometry. Benson LM, Vaughn JL, Strauch MA, Bobay BG, Thompson R, Naylor S, & Cavanagh J. Anal Biochem (2002) 306, 2: 222-7 [pubmed] [pdf]